Pulegone
Pulegone API
Pulegone (molecular formula: C₁₀H₁₆O) is a monoterpene ketone compound derived from natural plant essential oils, which is widely found in mint (Mentha), verbena (Verbena) and related plants. As a natural ingredient with aromaticity and high biological activity, Pulegone has received extensive attention in the fields of natural medicines, botanical pesticides, functional daily chemicals and pharmaceutical raw materials in recent years.
The Pulegone API we provide is a high-purity compound obtained through an efficient separation and purification process, which meets the quality standards of pharmaceutical or industrial grades and is suitable for a variety of uses such as scientific research and development and intermediate synthesis.
Research background and pharmacological effects
1. Anti-inflammatory effect
A large number of animal and cell experimental studies have found that Pulegone can inhibit the release of pro-inflammatory factors (such as TNF-α, IL-1β and IL-6), regulate COX-2 and NF-κB signaling pathways, and thus show significant anti-inflammatory potential in disease models such as rheumatoid arthritis and skin inflammation.
2. Analgesic and sedative effects
Pulegone has a certain inhibitory effect on the central nervous system and shows obvious analgesic effect in animal models. Its mechanism may be related to the regulation of the GABA neurotransmitter system. It has the potential to be used as an adjuvant treatment for mild anxiety or neuropathic pain.
3. Antibacterial and antifungal activity
Pulegone has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria, such as Staphylococcus aureus, Escherichia coli, Bacillus subtilis, etc.; it also shows inhibitory ability against fungi such as Candida albicans and Aspergillus, and is suitable for the development of natural preservatives and plant-based anti-infective products.
4. Insect repellent and insecticidal function
Due to its inhibitory effect on the insect nervous system, Pulegone is widely used in natural plant insect repellents, which can effectively repel mosquitoes, mites, fruit flies, etc., and has good ecological compatibility and biodegradability.
5. Potential anti-tumor activity (preliminary research)
Preliminary studies have shown that Pulegone may have an inhibitory effect on some tumor cells (such as breast cancer cells) by inducing apoptosis, regulating oxidative stress and mitochondrial function, etc., which provides a basis for the research of natural anti-cancer lead compounds.
Application fields and expected effects
● Pharmaceutical industry
As a natural lead molecule in drug development, Pulegone can be used as an intermediate to participate in the synthesis of menthol (Menthol), menthone, flavor additives and potential anti-inflammatory and antibacterial new drugs. It has broad application prospects in the modernization of traditional Chinese medicine and natural drug preparations.
● Cosmetics and daily chemicals
With its aromaticity and antibacterial activity, Pulegone is used to prepare natural mouthwashes, mouthwashes, antiseptic washes, mite sprays, mosquito repellent products, etc., to meet the market demand for green, low-irritation, and high-safety daily chemicals.
● Agriculture and environmentally friendly insect repellents
Pulegone, as a natural insecticide ingredient, is used to develop plant-based pesticides required for organic agriculture, reduce environmental pollution, improve crop quality, and comply with the sustainable agricultural development strategy.
Gentolex Group's quality commitment
The Pulegone API provided by our Gentolex Group has the following quality assurances:
High purity: purity ≥99%, suitable for pharmaceutical and high-end industrial use
Complies with GMP and ISO quality management system requirements
Provide comprehensive quality inspection reports (COA, including GC/HPLC analysis, heavy metals, residual solvents, microbial limits)
Customized specifications can be provided according to customer needs, supporting supply from grams to kilograms
