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Teriparatide Acetate API for Osteoporosis CAS NO.52232-67-4

Short Description:

Teriparatide is a synthetic 34-peptide, a 1-34 amino acid fragment of human parathyroid hormone PTH, which is the biologically active N-terminal region of the 84 amino acids endogenous parathyroid hormone PTH. The immunological and biological properties of this product are exactly the same as those of endogenous parathyroid hormone PTH and bovine parathyroid hormone PTH (bPTH).

Product Detail

Product Tags

Product Detail

Name  Teriparatide Acetate
Cas No.  52232-67-4Molecular
Formula  C181h291n55o51s2
Appearance  white to off white
Delivery Time  Ready in Stock
Package  Aluminum Foil Bag
Purity  ≥98%
Storage 2-8 degree
Transportation  Cold chain and cool storage delivery




Teriparatide can mediate bone metabolism by inhibiting osteoblast apoptosis, activating bone lining cells, and enhancing osteoblast differentiation. Intermittently stimulates the PHT-I receptor on the surface of osteoblasts, bone lining cells and bone marrow stromal stem cells by regulating the adenylate cyclase-cyclic adenosine monophosphate-protein kinase A pathway to promote osteoblast differentiation and prolong osteogenesis cell lifespan; Stimulates the proliferation of osteoblast cell lines through the phosphate C-cytoplasmic calcium-protein Chemicalbook kinase C signaling pathway; By inhibiting the transactivation activity of PPARγ, it reduces the differentiation of stromal cells to adipocyte lineage and increases the number of osteoblasts; Indirectly regulate bone growth by regulating cytokines, for example, iGF-1 can be induced to bind to osteoblasts, thereby promoting bone formation;

The process of bone formation is regulated by the Wnt signaling pathway, thereby increasing bone formation.


Can you supply the relevant documentation?

Yes, we can provide most documentation including Certificates of Analysis / Conformance; Insurance; Origin, and other export documents where required.

Quality System

In general, quality system and assurance is in place covering all stage of production of the finished product. Adequate manufacturing and control operations are performed in compliance with the approved procedures/ specifications. Change control and Deviation handling system is in place, and necessary impact assessment and investigation were conducted. Proper procedures are in place to ensure quality of product prior to release into the market.

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