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RU-58841 Used as Hair Loss Prevention and Male Pattern Baldness

Short Description:


Name:RU 58841

CAS number: 154992-24-2

Molecular formula: C17H18F3N3O3

Molecular weight: 369.34

EINECS Number: 1592732-453-0

Product Detail

Product Tags

Product Detail

Name  RU-58841
CAS number  154992-24-2
Molecular formula  C17H18F3N3O3
Molecular weight  369.34
EINECS Number  1592732-453-0
Boiling Point  493.6±55.0 °C(Predicted)
Density  1.39
Storage condition  Sealed in dry,Store in freezer, under -20°C
Form  Powder
Color  White
Packing  PE bag+Aluminum bag



Pharmacological Effect


RU 58841 (PSK-3841) is an androgen receptor antagonist that promotes hair regrowth. RU58841 is an investigational drug created for treatment against androgenic alopecia, also known as male pattern baldness(MPD).

As a topical anti-androgen, its principle of action is not the same as that of finasteride. Finasteride directly acts on 5α reductase, inhibits the conversion of testosterone into DHT, and reduces the content of DHT in the body. RU58841 blocks the contact between dihydrotestosterone and hair follicle receptors, it does not directly reduce DHT content, but it reduces the binding of DHT and hair follicle receptors, so as to achieve the purpose of treating androgenetic alopecia.

4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile can be used as medicine Chemical synthesis intermediates.If 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile is inhaled, Move the patient to fresh air; In case of skin contact, remove contaminated clothing, rinse skin thoroughly with soap and water, and seek medical attention if discomfort occurs;


Side Effect

RU58841 is applied to the scalp, absorbed by the hair follicles, and theoretically, it can enter the bloodstream and affect other parts of the body. But no systemic side effects have been found in studies of topical application in monkeys. However, some people who have tried RU58841 claim they have experienced some possible side effects from using RU, including skin irritation, decreased libido, erectile dysfunction, nausea, red eyes, dizziness, and headache.


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