Wholesale Price China Rare Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:

Send email to us

Product Detail

Product Tags

Feedback (2)

We are proud of the high customer satisfaction and wide acceptance due to our persistent pursuit of high quality both on product and service for Chlorpheniramine Maleate Ammonium Chloride, Diphenylacetonitrile Uses, Dicocodimonium Chloride, Only for accomplish the good-quality product or service to satisfy customer's demand, all of our products have been strictly inspected before shipment.

Wholesale Price China Rare Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name	N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number	14636-12-5
Molecular formula	C52H74N16O15S2
Molecular weight	1227.37
EINECS Number	238-680-8
Boiling point	1824.0±65.0 °C (Predicted)
Density	1.46±0.1 g/cm3(Predicted)
Storage conditions	Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient	(pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.

Product detail pictures:

Related Product Guide:

We goal to understand excellent disfigurement from the manufacturing and supply the top support to domestic and abroad clients wholeheartedly for Wholesale Price China Rare Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Montpellier, European, Swansea, "Good quality, Good service " is always our tenet and credo. We take every effort to control the quality, package, labels etc and our QC will check every detail during producing and before shipment. We are willing to establish long business relationship with those who seek the high quality products and good service. We have set up a wide sales network across European countries, North of America, South of America, Middle East, Africa, East Asia countries.Please contact us now, you will find our professional experience and high quality grades will contribute to your business.

Benzocaine