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Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Featured Image
  • Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

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Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

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Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.

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Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

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With sophisticated technologies and facilities, strict top quality handle, reasonable value, exceptional support and close co-operation with clients, we are devoted to furnishing the ideal worth for our clients for Wholesale Dealers of Essential Amino Acids - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Colombia, Nicaragua, Morocco, As a way to use the resource on the expanding info in international trade, we welcome prospects from everywhere on the web and offline. In spite on the high quality objects we offer you, effective and satisfying consultation service is supplied by our qualified after-sale service group. Item lists and in depth parameters and any other info weil be sent to you timely for the inquiries. So you should make contact with us by sending us emails or call us when you've got any questions about our organization. ou could also get our address information from our site and come to our enterprise. We get a field survey of our merchandise. We're confident that we are going to share mutual accomplishment and create solid co-operation relations with our companions within this market place. We're seeking forward for your inquiries.
    • In general, we are satisfied with all aspects, cheap, high-quality, fast delivery and good procuct style, we will have follow-up cooperation!
    5 Stars By Myra from Angola - 2017.12.09 14:01
    Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
    5 Stars By Roberta from Mauritius - 2017.09.16 13:44
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