Wholesale Cypopnate - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex

Short Description:

Send email to us

Product Detail

Product Tags

Feedback (2)

Our company insists all along the quality policy of "product good quality is base of enterprise survival; buyer fulfillment will be the staring point and ending of an company; persistent improvement is eternal pursuit of staff" and also the consistent purpose of "reputation very first, shopper first" for Sebacic Acid Di-N-Octyl Ester 2432-87-3, Plumbous Acetate, 125541-22-2, We have a professional team for international trade. We can solve the problem you meet. We can provide the products you want. Please feel free to contact us.

Wholesale Cypopnate - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex Detail:

Product Detail

Name	Leuprorelin
CAS number	53714-56-0
Molecular formula	C59H84N16O12
Molecular weight	1209.4
EINECS Number	633-395-9
Specific rotation	D25 -31.7° (c = 1 in 1% acetic acid)
Density	1.44±0.1 g/cm3(Predicted)
Storage condition	-15°C
Form	Neat
Acidity coefficient	(pKa) 9.82±0.15 (Predicted)
Water solubility	Soluble in water at 1mg/ml

Synonyms

LH-RHLEUPROLIDE;LEUPROLIDE;LEUPROLIDE(HUMAN);LEUPRORELIN;[DES-GLY10,D-LEU6,PRO-NHET9]-LUTEINIZINGHORMONE-RELEASINGHORMONEHUMAN;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGHORMONE;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGFACTOR;[DES-GLY10,D-LEU6,PRO-NHET9]-LH-RH(HUMAN)

Pharmacological Effect

Leuprolide, goserelin, triprelin, and nafarelin are several drugs commonly used in clinical practice to remove ovaries for the treatment of premenopausal breast cancer and prostate cancer. (referred to as GnRH-a drugs), GnRH-a drugs are similar in structure to GnRH and compete with pituitary GnRH receptors. That is, the gonadotropin secreted by the pituitary decreases, which leads to a significant decrease in the sex hormone secreted by the ovary.

Leuprolide is a gonadotropin-releasing hormone (GnRH) analog, a peptide composed of 9 amino acids. This product can effectively inhibit the function of the pituitary-gonadal system, the resistance to proteolytic enzymes and the affinity to the pituitary GnRH receptor are stronger than GnRH, and the activity of promoting the release of luteinizing hormone (LH) is about 20 times that of GnRH. It also has a stronger inhibitory effect on pituitary-gonad function than GnRH. In the initial stage of treatment, follicle stimulating hormone (FSH), LH, estrogen or androgen may be temporarily increased, and then, due to the decreased responsiveness of the pituitary gland, the secretion of FSH, LH and estrogen or androgen is inhibited, resulting in dependence on sex hormones. Sexual diseases (such as prostate cancer, endometriosis, etc.) have a therapeutic effect.

At present, the acetate salt of leuprolide is mainly used clinically, because the performance of leuprolide acetate is more stable at room temperature. Liquid should be discarded. It can be used for the drug castration treatment of endometriosis and uterine fibroids, central precocious puberty, premenopausal breast cancer and prostate cancer, and also for functional uterine bleeding that is contraindicated or ineffective for conventional hormone therapy. It can also be used as a premedication before endometrial resection, which can evenly thin the endometrium, reduce edema, and reduce the difficulty of surgery.

Product detail pictures:

Related Product Guide:

Together with the "Client-Oriented" enterprise philosophy, a arduous good quality control technique, sophisticated producing equipment and a sturdy R&D staff, we generally offer superior quality merchandise, superb solutions and aggressive rates for Wholesale Cypopnate - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex , The product will supply to all over the world, such as: Czech Republic, Cancun, USA, Our main objectives are to provide our customers worldwide with good quality, competitive price, satisfied delivery and excellent services. Customer satisfaction is our main goal. We welcome you to visit our showroom and office. We are looking forward to establish business relation with you.

Butylcyclohexyl Acetate