CJC-1295 is a synthetic peptide that functions as a growth hormone–releasing hormone (GHRH) analog — meaning it stimulates the body’s natural release of growth hormone (GH) from the pituitary gland.
Here’s a detailed overview of its functions and effects:
Mechanism of Action
CJC-1295 binds to GHRH receptors in the pituitary gland.
This triggers pulsatile release of growth hormone (GH).
It also increases insulin-like growth factor 1 (IGF-1) levels in the blood, which mediates many of GH’s anabolic effects.
Main Functions & Benefits
1. Increases Growth Hormone and IGF-1 Levels
- Enhances metabolism, fat loss, and muscle recovery.
- Supports tissue repair and regeneration.
2. Promotes Muscle Growth and Recovery
- GH and IGF-1 help increase protein synthesis and lean body mass.
- May reduce recovery time between workouts or injuries.
3. Enhances Fat Metabolism
- Encourages lipolysis (fat breakdown) and reduces body fat percentage.
4. Improves Sleep Quality
- GH secretion peaks during deep sleep; CJC-1295 may improve sleep depth and recovery quality.
5. Supports Anti-Aging Effects
- GH and IGF-1 can improve skin elasticity, energy levels, and overall vitality.
Pharmacological Notes
- CJC-1295 with DAC (Drug Affinity Complex) has an extended half-life of up to 6–8 days, allowing once- or twice-weekly dosing.
- CJC-1295 without DAC has a much shorter half-life and is usually used in research combinations (e.g., with Ipamorelin) for daily administration.
For Research Use
CJC-1295 is used in research settings to study:
- GH regulation
- Age-related hormone decline
- Metabolic and muscle regeneration mechanisms
(Not approved for human therapeutic use outside clinical research.)
Post time: Oct-14-2025