Newly Arrival Mirabegron - Atosiban Acetate Used for Anti Premature Birth – Gentolex
Newly Arrival Mirabegron - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:
Product Detail
| Name | Atosiban |
| CAS number | 90779-69-4 |
| Molecular formula | C43H67N11O12S2 |
| Molecular weight | 994.19 |
| EINECS Number | 806-815-5 |
| Boiling point | 1469.0±65.0 °C (Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| Storage conditions | -20°C |
| Solubility | H2O:≤100 mg/mL |
Description
Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.
Application
Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.
Effect
Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.
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Our firm sticks to the basic principle of "Quality is the life of your company, and status will be the soul of it" for Newly Arrival Mirabegron - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Russia, Cairo, Mexico, We now have been making our goods for more than 20 years . Mainly do wholesale , so we've the most competitive price , but highest quality. For the past years , we got very good feedbacks , not only because we offer good solutions , but also because of our good after-sale service . We are here waiting for yourself for your inquiry.
By Marguerite from Iraq - 2017.11.29 11:09
The company leader recept us warmly, through a meticulous and thorough discussion, we signed a purchase order. Hope to cooperate smoothly
By Andrew from Italy - 2018.06.30 17:29
