Good Quality 3′-Methoxypropiophenone - Atosiban Acetate Used for Anti Premature Birth – Gentolex
Good Quality 3′-Methoxypropiophenone - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:
Product Detail
| Name | Atosiban |
| CAS number | 90779-69-4 |
| Molecular formula | C43H67N11O12S2 |
| Molecular weight | 994.19 |
| EINECS Number | 806-815-5 |
| Boiling point | 1469.0±65.0 °C (Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| Storage conditions | -20°C |
| Solubility | H2O:≤100 mg/mL |
Description
Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.
Application
Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.
Effect
Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.
Product detail pictures:
Related Product Guide:
We usually continually offer you the most conscientious consumer services, along with the widest variety of designs and styles with finest materials. These initiatives include the availability of customized designs with speed and dispatch for Good Quality 3′-Methoxypropiophenone - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Plymouth, Porto, US, With the advanced workshop, professional design team and strict quality control system, based on mid- to high-end marked as our marketing positioning, our products are fast selling onto European and American markets with our own brands such as below Deniya, Qingsiya and Yisilanya.
By Melissa from UK - 2017.05.21 12:31
Company director has very rich management experience and strict attitude, sales staff are warm and cheerful, technical staff are professional and responsible,so we have no worry about product,a nice manufacturer.
By Laura from Australia - 2017.06.22 12:49
