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Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex Featured Image
  • Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex

Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex

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With reliable quality process, good reputation and perfect customer service, the series of products produced by our company are exported to many countries and regions for 4-Methoxyphenylacetic Acid, Benzalkonium Chloride Antiseptic, Carbobenzoxy Chloride, With a rapid advancement and our buyers come from Europe, United States, Africa and everywhere in the world. Welcome to visit our manufacturing unit and welcome your order, for further more inquires be sure to don't hesitate to get hold of us!
Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex Detail:

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Name  Leuprorelin
CAS number  53714-56-0
Molecular formula  C59H84N16O12
Molecular weight  1209.4
EINECS Number  633-395-9
Specific rotation  D25 -31.7° (c = 1 in 1% acetic acid)
Density  1.44±0.1 g/cm3(Predicted)
Storage condition  -15°C
Form  Neat
Acidity coefficient  (pKa) 9.82±0.15 (Predicted)
Water solubility  Soluble in water at 1mg/ml

Synonyms

LH-RHLEUPROLIDE;LEUPROLIDE;LEUPROLIDE(HUMAN);LEUPRORELIN;[DES-GLY10,D-LEU6,PRO-NHET9]-LUTEINIZINGHORMONE-RELEASINGHORMONEHUMAN;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGHORMONE;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGFACTOR;[DES-GLY10,D-LEU6,PRO-NHET9]-LH-RH(HUMAN)

Pharmacological Effect

Leuprolide, goserelin, triprelin, and nafarelin are several drugs commonly used in clinical practice to remove ovaries for the treatment of premenopausal breast cancer and prostate cancer. (referred to as GnRH-a drugs), GnRH-a drugs are similar in structure to GnRH and compete with pituitary GnRH receptors. That is, the gonadotropin secreted by the pituitary decreases, which leads to a significant decrease in the sex hormone secreted by the ovary.

Leuprolide is a gonadotropin-releasing hormone (GnRH) analog, a peptide composed of 9 amino acids. This product can effectively inhibit the function of the pituitary-gonadal system, the resistance to proteolytic enzymes and the affinity to the pituitary GnRH receptor are stronger than GnRH, and the activity of promoting the release of luteinizing hormone (LH) is about 20 times that of GnRH. It also has a stronger inhibitory effect on pituitary-gonad function than GnRH. In the initial stage of treatment, follicle stimulating hormone (FSH), LH, estrogen or androgen may be temporarily increased, and then, due to the decreased responsiveness of the pituitary gland, the secretion of FSH, LH and estrogen or androgen is inhibited, resulting in dependence on sex hormones. Sexual diseases (such as prostate cancer, endometriosis, etc.) have a therapeutic effect.

At present, the acetate salt of leuprolide is mainly used clinically, because the performance of leuprolide acetate is more stable at room temperature. Liquid should be discarded. It can be used for the drug castration treatment of endometriosis and uterine fibroids, central precocious puberty, premenopausal breast cancer and prostate cancer, and also for functional uterine bleeding that is contraindicated or ineffective for conventional hormone therapy. It can also be used as a premedication before endometrial resection, which can evenly thin the endometrium, reduce edema, and reduce the difficulty of surgery.

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Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex detail pictures

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Reliable good quality and very good credit standing are our principles, which will help us at a top-ranking position. Adhering to your tenet of "quality 1st, purchaser supreme" for Factory making N-Methyl-N-((3r,4r)-4-Methylpiperidin-3-Yl)-7h-Pyrrolo[2,3-D]Pyrimidin-4-Amine - Orlistat 96829-58-2 Reducing Absorption of Sietary Fat, Resulting in Weight Loss – Gentolex , The product will supply to all over the world, such as: Argentina, Czech republic, Senegal, Insisting on the high quality generation line management and customers expert assistance, we now have designed our resolution to supply our buyers using the to start with amount getting and just after services practical experience. Maintaining the prevailing friendly relations with our buyers, we however innovate our solution lists all of the time to satisfy the brand new demands and adhere to the most up-to-date development of the market in Malta. We have been ready to face the worries and make the improve to understand all the possibilities in international trade.
    • This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.
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