Factory Free sample M1 Pseudouridine - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex
Factory Free sample M1 Pseudouridine - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex Detail:
Product Detail
| Name | Daptomycin |
| CAS number | 103060-53-3 |
| Molecular formula | C72H101N17O26 |
| Molecular weight | 1620.67 |
| EINECS Number | 600-389-2 |
| Melting point | 202-204°C |
| Boiling point | 2078.2±65.0 °C (Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| Flash point | 87℃ |
| Storage conditions | Sealed in dry, Store in freezer, under -20°C |
| Solubility | Methanol:soluble5mg/mL |
| Acidity coefficient | (pKa) 4.00±0.10 (Predicted) |
| Form | powder |
| Color | colorless to faint yellow |
Synonyms
N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone;DAPTOMYCINE;Dapcin;Daptomycin,>=99%;DaptomycinReadyMadeSolution;Daptomycin(LY146032)
Description
The antibiotic daptomycin is a cyclic lipopeptide antibiotic with a new structure extracted from the fermentation broth of Streptomyces (S. reseosporus), which hinders the biosynthesis of bacterial cell wall peptidoglycan by disturbing the transport of amino acids in the cell membrane. Altering the properties of the cytoplasmic membrane can disrupt bacterial membrane function in multiple ways and rapidly kill Gram-positive bacteria. In addition to its ability to act on most clinically relevant Gram-positive bacteria, daptomycin is more important for isolated strains that have shown resistance to methicillin, vancomycin, and linezolid in vitro. It has potent activity, and this property has very important clinical implications for critically ill infected patients. Eosinophilic pneumonia is a rare and very serious disease with symptoms including fever, cough, shortness of breath, and difficulty breathing.
Antibacterial Effect
Daptomycin has good bacteriostatic activity against various antibiotic-resistant bacteria, such as MIC=0.06-0.5 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-resistant Staphylococcus aureus (MRSA). MIC=0.0625～1μg/ml for bacteria, MIC=0.12～0.5μg/ml for oxacillin-resistant Staphylococcus epidermidis, MIC=2.5μg/ml for enterococcus highly resistant to aminoglycoside antibiotics, MIC=2.5μg/ml for GmrBIa -The MIC of Enterococcus is 0.5～1μg/ml, and the MIC of Enterococcus resistant to glycopeptide antibiotics is 1～2μg/ml.
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Using a complete scientific top quality management program, great high-quality and fantastic religion, we win great track record and occupied this area for Factory Free sample M1 Pseudouridine - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex , The product will supply to all over the world, such as: Vietnam, Algeria, Canada, We taking advantage of experience workmanship, scientific administration and advanced equipment, ensure the product quality of production, we not only win the customers' faith, but also build up our brand. Today, our team is committed to innovation, and enlightenment and fusion with constant practice and outstanding wisdom and philosophy, we cater to the market demand for high-end goods, to do experienced products and solutions.
By Sara from Luxembourg - 2018.12.25 12:43
The customer service staff is very patient and has a positive and progressive attitude to our interest, so that we can have a comprehensive understanding of the product and finally we reached an agreement, thanks!
By Pag from Mombasa - 2018.09.16 11:31
