Competitive Price for Plumbic Acetate - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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Competitive Price for Plumbic Acetate - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name	Atosiban
CAS number	90779-69-4
Molecular formula	C43H67N11O12S2
Molecular weight	994.19
EINECS Number	806-815-5
Boiling point	1469.0±65.0 °C (Predicted)
Density	1.254±0.06 g/cm3(Predicted)
Storage conditions	-20°C
Solubility	H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.

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The consumer fulfillment is our primary goal. We uphold a consistent level of professionalism, top quality, credibility and service for Competitive Price for Plumbic Acetate - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Naples, Hamburg, New Zealand, We insist on "Quality First, Reputation First and Customer First". We are committed to providing high-quality products and good after-sales services. Up to now, our products have been exported to more than 60 countries and areas around the world, such as America, Australia and Europe. We enjoy a high reputation at home and abroad. Always persisting in the principle of "Credit, Customer and Quality", we expect cooperation with people in all walks of life for mutual benefits.

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