Chinese Professional Amisulpride - Atosiban Acetate Used for Anti Premature Birth – Gentolex
Chinese Professional Amisulpride - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:
Product Detail
| Name | Atosiban |
| CAS number | 90779-69-4 |
| Molecular formula | C43H67N11O12S2 |
| Molecular weight | 994.19 |
| EINECS Number | 806-815-5 |
| Boiling point | 1469.0±65.0 °C (Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| Storage conditions | -20°C |
| Solubility | H2O:≤100 mg/mL |
Description
Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.
Application
Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.
Effect
Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.
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We attempt for excellence, company the customers", hopes to be the top cooperation team and dominator company for personnel, suppliers and customers, realizes price share and continual marketing for Chinese Professional Amisulpride - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Malta, Ottawa, Slovenia, By integrating manufacturing with foreign trade sectors, we can present total customer solutions by guaranteeing the delivery of right merchandise to the right place at the right time, which is supported by our abundant experiences, powerful production capability, consistent quality, diversified products and the control of the industry trend as well as our maturity before and after sales services. We'd like to share our ideas with you and welcome your comments and questions.
By Mike from Malawi - 2018.02.08 16:45
This is the first business after our company establish, products and services are very satisfying, we have a good start, we hope to cooperate continuous in the future!
By Grace from Somalia - 2018.07.26 16:51
