English
  • head_banner_01
China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Featured Image
  • China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

With advanced technologies and facilities, strict good quality manage, reasonable rate, superior assistance and close co-operation with shoppers, we have been devoted to supplying the very best price for our consumers for Acetate De Zinc, Vanadium Acetate, Acetyl Tributyl Citrate 77-90-7, We have now deep cooperation with hundreds of factories all over China. The goods we give can match with your different calls for. Choose us, and we won't make you regret!
China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.

Product detail pictures:

China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Related Product Guide:
To meet the customers' over-expected gratification , we have our robust crew to offer our best over-all support which includes marketing, income, coming up with, production, excellent managing, packing, warehousing and logistics for China Supplier Aceto Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Lisbon, Lahore, Turin, Please feel cost-free to send us your specifications and we'll respond to you asap. We've got a professional engineering team to serve for the every single detailed needs. Free samples may be sent for you personally to know far more facts. So that you can meet your desires, please really feel cost-free to contact us. You could send us emails and call us straight. Additionally, we welcome visits to our factory from all over the world for much better recognizing of our corporation. nd merchandise. In our trade with merchants of several countries, we often adhere to the principle of equality and mutual advantage. It is our hope to market, by joint efforts, both trade and friendship to our mutual benefit. We look forward to getting your inquiries.
    • This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
    5 Stars By Ivy from Rome - 2017.09.09 10:18
    The product manager is a very hot and professional person, we have a pleasant conversation, and finally we reached a consensus agreement.
    5 Stars By Dolores from Bandung - 2017.11.29 11:09
    Write your message here and send it to us

    Related PRODUCTS

    Hit enter to search or ESC to close