BPC-157
BPC-157 API
BPC-157 (full name: Body Protection Compound 157) is a synthetic short peptide composed of 15 amino acids, derived from a sequence of natural protective proteins in human gastric juice. It has shown extensive tissue repair and anti-inflammatory capabilities in experimental studies and is widely regarded as a highly promising multifunctional peptide drug candidate.
As an active pharmaceutical ingredient (API), BPC-157 has been used in many scientific research fields around the world to explore its biological activity in the gastrointestinal tract, musculoskeletal system, nervous system, cardiovascular system and soft tissue repair, especially in trauma repair and anti-inflammatory research.
Research and pharmacological mechanism of action
BPC-157 has been widely studied, especially in in vivo animal experiments and in vitro cell models, and it has been found to have the following core pharmacological effects:
1. Tissue regeneration and trauma repair
Promotes tendon, ligament, bone and soft tissue regeneration, and can enhance angiogenesis (angiogenesis).
Accelerate wound healing, postoperative repair and recovery of soft tissue injuries, which has been verified in animal models such as tendon rupture, muscle strain, and fracture.
2. Gastrointestinal protection and repair
In models such as gastric ulcer, enteritis, and colitis, BPC-157 has a significant mucosal protective effect.
It can resist gastrointestinal damage caused by nonsteroidal anti-inflammatory drugs (NSAIDs) and promote intestinal mucosal healing.
3. Anti-inflammatory and immunomodulatory
It regulates the balance of the immune system by inhibiting pro-inflammatory factors (such as TNF-α, IL-6) and upregulating anti-inflammatory factors.
It has potential value as an auxiliary treatment for chronic inflammatory diseases such as **rheumatoid arthritis and inflammatory bowel disease (IBD)**.
4. Neuroprotection and neuroregeneration
In models after spinal cord injury, nerve contusion, and cerebrovascular events, BPC-157 can promote nerve regeneration and reduce nerve damage.
It can fight against problems in the neuropsychiatric field such as anxiety, depression, and alcohol dependence (experimental stage).
5. Cardiovascular and vascular protection
BPC-157 can improve vascular permeability and promote microvascular repair, and is believed to have a positive effect on diseases such as myocardial ischemia, venous thrombosis, and arterial injury.
Experimental and preclinical research results
Although BPC-157 has not yet been widely approved for human prescription drugs, it has shown in animal experiments:
Significant acceleration of tissue repair time (such as 50% acceleration of tendon healing)
Significantly reduce the incidence of gastric bleeding, intestinal injury, and colon ulcers
Improve nerve conduction recovery and enhance the function of the innervated area
Increase angiogenesis and granulation tissue formation rate
Due to these results, BPC-157 is becoming an important research candidate molecule in the fields of post-traumatic rehabilitation, sports injuries, gastrointestinal diseases, and neurodegenerative diseases.
API production and quality control
The BPC-157 API provided by our Gentolex Group adopts solid phase synthesis (SPPS) process and is produced under GMP conditions. It has the following characteristics:
High purity: ≥99% (HPLC detection)
Low impurity residue, no endotoxin, no heavy metal pollution
Batch stability, strong repeatability, support injection level use
Support gram and kilogram level supply to meet the needs of different stages from R&D to industrialization.
