English
  • head_banner_01
Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Featured Image
  • Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

We have been also concentrating on enhancing the things management and QC method so that we could preserve terrific edge inside the fiercely-competitive enterprise for Sildenafil, 2,4-Dimethyl-5-Pyrimidinol, Cas 16056-11-4, We have exported to more than 40 countries and regions, which have gained good reputation from our costumers all over the world.
Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.

Product detail pictures:

Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Related Product Guide:
Our personnel are generally in the spirit of "continuous improvement and excellence", and together with the outstanding top quality merchandise, favorable price tag and fantastic after-sales solutions, we try to gain every single customer's rely on for Bottom price Lithium Bromide 7550-35-8 - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Mongolia, Uzbekistan, Doha, Faced with the vitality of the global wave of economic integration, we are confident with our high-quality products and sincerely service to all our customers and wish we can cooperate with you to create a brilliant future.
    • The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
    5 Stars By Donna from Borussia Dortmund - 2018.12.28 15:18
    The company can think what our think, the urgency of urgency to act in the interests of our position, can be said this is a responsible company, we had a happy cooperation!
    5 Stars By Eleanore from Greece - 2018.10.31 10:02
    Write your message here and send it to us

    Related PRODUCTS

    Hit enter to search or ESC to close